Activity of the Mouse CD 72 Promoter PU . 1 / Spi - 1 Is Essential for the B Cell - Specific
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منابع مشابه
PU.1/Spi-1 is essential for the B cell-specific activity of the mouse CD72 promoter.
CD72 is a 45-kDa glycoprotein that is predominantly expressed on cells of the B lineage, except for plasma cells. Its expression pattern is representative of many B cell-specific proteins, which are essential for B cell development and activation but are down-regulated after B cells become terminally differentiated plasma cells. We have examined the promoter region of the mouse CD72 gene to ide...
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